| Date | Home/Away | Push-Back | Opponents | Meet Up | Pitch/Details | Result H - A | Scorers |
| 11 Sep 10 | Away | | Yeovil & Sherborne C | | The Gryphon School | | |
| 18 Sep 10 | Away | | Gillingham A | | | | |
| 25 Sep 10 | Home | 16.00 | Mid Somerset A | | The Gryphon School | | |
| 02 Oct 10 | Home | 16.00 | Minehead A | *Colour Clash-visitors to change* | The Gryphon School | | |
| 09 Oct 10 | Away | 15.00 | East Devon B | | West Exe Technology College | | |
| 16 Oct 10 | Home | 14.30 | Chard A | | The Gryphon School | | |
| 23 Oct 10 | Away | 15.00 | Isca C | **Colour Clash** | University of Exeter Sports Park - Sand Astro | | |
| 30 Oct 10 | Home | 14.30 | Yeovil & Sherborne A | **Colour Clash-visitors change** | The Gryphon School | | |
| 06 Nov 10 | Away | 15.30 | ECV Hornets C | | St Peters School | | |
| 13 Nov 10 | Home | 16.00 | Teign | | The Gryphon School | | |
| 20 Nov 10 | Away | | Ashmoor A | | Isca College | | |
| 27 Nov 10 | Home | 14.30 | North Devon A | | The Gryphon School | | |
| 04 Dec 10 | Away | 13.00 | Okehampton | | Okehampton College | | |
| 11 Dec 10 | Away | 14.30 | Mid Somerset A | | Wells Blue School | | |
| 18 Dec 10 | Home | 13.00 | Gillingham A | | The Gryphon School | | |
| 15 Jan 11 | Home | 14.30 | West Wilts C | | The Gryphon School | | |
| 22 Jan 11 | Away | | Minehead A | **Colour Clash** | West Somerset Leisure Centre | | |
| 29 Jan 11 | Home | 16.00 | East Devon B | | The Gryphon School | | |
| 05 Feb 11 | Away | 14.00 | Chard A | | Holyrood School | | |
| 12 Feb 11 | Home | 14.30 | Isca C | *Colour Clash-visitors to change* | The Gryphon School | | |
| 19 Feb 11 | Away | 13.00 | Yeovil & Sherborne A | **Colour Clash** | The Gryphon School | | |
| 26 Feb 11 | Home | 14.30 | EVC Hornets C | | The Gryphon School | | |
| 05 Mar 11 | Away | 15.00 | Teign | | Dawlish Leisure Centre | | |
| 12 Mar 11 | Home | 14.30 | Ashmoor A | | The Gryphon School | | |
| 19 Mar 11 | Away | 14.00 | North Devon A | | Park School | | |
| 26 Mar 11 | Home | 16.00 | Okehampton | | The Gryphon School | | |