| Date | Home/Away | Push-Back | Opponents | Meet Up | Pitch/Details | Result H - A | Scorers |
| 11 Sep 10 | Home | 11.30 | Yeovil & Sherborne B | | The Gryphon School | | |
| 18 Sep 10 | Home | 16.00 | Gillingham B | | The Gryphon School | | |
| 25 Sep 10 | Away | 13.00 | Sidmouth B | | Sidmouth Community College | | |
| 02 Oct 10 | Away | 16.30 | Taunton Vale D | | Taunton Vale Sports Club | | |
| 09 Oct 10 | Home | 14.30 | Isca D | *Colour Clash-visitors to change* | The Gryphon School | | |
| 16 Oct 10 | Away | 15.30 | Ottery Crickets C | | Colin Tooze Sports Centre | | |
| 23 Oct 10 | Home | 14.30 | ECV Hornets D | | The Gryphon School | | |
| 30 Oct 10 | Away | 13.00 | Bridgwater C | | Chilton Trinity School | | |
| 06 Nov 10 | Home | 16.00 | Torbay B | | The Gryphon School | | |
| 13 Nov 10 | Away | 15.00 | Teign A | | Dawlish Leisure Centre | | |
| 20 Nov 10 | Home | 16.00 | Ottery Crickets B | | The Gryphon School | | |
| 27 Nov 10 | Away | | West Dorset A | | Colfox School | | |
| 04 Dec 10 | Home | 14.30 | Bridgwater B | | The Gryphon School | | |
| 11 Dec 10 | Home | 16.00 | Sidmouth B | | The Gryphon School | | |
| 18 Dec 10 | Away | | Gillingham B | | | | |
| 15 Jan 11 | Away | | West Wilts D | | | | |
| 22 Jan 11 | Home | 14.30 | Taunton Vale D | | The Gryphon School | | |
| 29 Jan 11 | Away | 16.30 | Isca D | **COLOUR CLASH** | University of Exeter Sports Park - Sand Astro | | |
| 05 Feb 11 | Home | 16.00 | Ottery Crickets C | | The Gryphon School | | |
| 12 Feb 11 | Away | 12.30 | ECV Hornets D | | Culm Valley Sports Centre | | |
| 19 Feb 11 | Home | 16.00 | Bridgwater C | | The Gryphon School | | |
| 26 Feb 11 | Away | 15.45 | Torbay B | | Torquay Girls Grammer School | | |
| 05 Mar 11 | Home | 14.30 | Teign A | | The Gryphon School | | |
| 12 Mar 11 | Away | 15.30 | Ottery Crickets B | | Colin Tooze Sports Centre | | |
| 19 Mar 11 | Home | 16.00 | West Dorset A | | The Gryphon School | | |
| 26 Mar 11 | Away | 11.30 | Bridgwater B | | Chilton Trinity School | | |